![]() This can be a life-threatening situation. Known as a pulmonary embolism, this occurs when a portion of a DVT breaks free and travels through the right side of your heart to your lung, where it blocks blood flow. If signs and symptoms do occur, they can include: This is known as deep vein thrombosis (DVT), which most commonly occurs in the legs. Symptoms of a blood clot depend on what part of your body is affected. ![]() Some clots do no damage and disappear on their own. Since factor V Leiden is a risk for developing blood clots in the leg or lungs, the first indication that you have the disorder may be the development of an abnormal blood clot. The factor V Leiden mutation does not itself cause any symptoms.
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